» full cast
| Astro | Don Messick |
| Arthur Spacely | Dick Beals |
| Celeste Skyler | Bea Benaderet |
| Commissioner | John Stephenson |
| Construction Worker | Allan Melvin |
| Cousin Melissa | Didi Conn |
| Curly Quasar | Gregg Berger |
| DJ | Brian Cummings |
| Dr. Input | Paul Winchell |
| Elroy Jetson | Daws Butler |
| Florist | Lorenzo Music |
| George Jetson | George O'Hanlon |
| Hall Monitor | Rob Paulsen |
| Harlan | Howard Morris |
| Jane Jetson | Penny Singleton |
| Judy Jetson | Janet Waldo |
| Jupiter Juggernaut | Peter Cullen |
| Lenny Laser | Barry Gordon |
| Mr. Rocket | Sonny Melendrez |
| Mr. Spacely | Mel Blanc |
| Orbitty | Frank Welker |
| Ralph | Frank Nelson |
| Randy | Dan Gilvezan |
| Robot | B.J. Ward |
| Rosie the Robot | Jean Vander Pyl |
| Sam Spacely | Roger DeWitt |
| School Patrol robots, Executive Vice President | Phil Hartman |
| Wink Martiandale | Wink Martindale |